Reply To: 15 year old boy with Alopecia Areata

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#823
Christine Bailey
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Dear Nathalie,

Many thanks for your question about your client who is suffering with hair loss at a young age. You have already identified a lot of key links and I agree with you that a stool test would be recommended. I would also suggest looking at the Cyrex testing – arrays 3 and 4 as these are particularly helpful when autoimmune conditions are evident. However, these would not be possible if the client is taking steroids as these will interfere with the results.

Alopecia areata, an autoimmune condition in which the immune system attacks hair follicles, can affect children and adults of both genders. It causes round patches of balding, mostly on the scalp and beard region.  This can be aggravated by hormone changes and this may explain why it is now noticeable as the boy goes through puberty.

In patients who opt for treatment, corticosteroids that suppress the underlying autoimmune process can be applied to affected areas either as cream or injections, and oral corticosteroids are used in some cases of extensive hair loss.

Qi J, Garza LA. An overview of alopecias. Cold Spring Harbor perspectives in medicine. Mar 2014;4(3). https://tinyurl.com/y8buxy5x

 

Various B vitamins can be helpful for hair growth. Forty-six women with diffuse alopecia received 200 mg per day of oral vitamin B5 plus daily intramuscular injections of vitamin B6 for 20–30 days. The treatment was repeated after six months and resulted in improved hair condition and reduced hair loss.

Brzezinska-Wcislo L. [Evaluation of vitamin B6 and calcium pantothenate effectiveness on hair growth from clinical and trichographic aspects for treatment of diffuse alopecia in women]. Wiadomosci lekarskie (Warsaw, Poland: 1960). 2001;54(1-2):11-18. https://tinyurl.com/y72t56ly

 

Some preliminary evidence suggests that biotin supplementation may help treat alopecia caused by the medication valproic acid.

Famenini S, Goh C. Evidence for supplemental treatments in androgenetic alopecia. J Drugs Dermatol. Jul 2014;13(7):809-812. https://tinyurl.com/yb95lu74

 

A growing body of evidence shows that vitamin D participates in regulation of the hair cycle (Amor 2010; Low serum vitamin D levels are associated with autoimmune disorders including alopecia areata.

Mahamid M, Abu-Elhija O, Samamra M, Mahamid A, Nseir W. Association between vitamin D levels and alopecia areata. The Israel Medical Association journal: IMAJ. Jun 2014;16(6):367-370. https://tinyurl.com/yaobme6w

 

Protein deficiency is a well-established cause of hair loss, and one protein, keratin, is the main component and primary structural element of hair so protein is important in the diet and yes, the collagen could be helpful.

Silicon, a trace element present in the body in small quantities, is thought to function as a structural component of hair.

Martin KR. Silicon: the health benefits of a metalloid. Metal ions in life sciences. 2013;13:451-473. https://tinyurl.com/y9regxxl

 

Lower zinc levels in patients with alopecia areata have been correlated with increased severity, longer duration, and higher likelihood of treatment resistance.

Bhat YJ, Manzoor S, Khan AR, Qayoom S. Trace element levels in alopecia areata. Indian journal of dermatology, venereology and leprology. Jan-Feb 2009;75(1):29-31. https://tinyurl.com/ybc9m5n5

 

Emerging evidence suggest tocotrienols may help promote healthy hair. In a study involving 38 women and men with various types and degrees of hair loss, those receiving supplements with 23 IU alpha-tocopherol plus 50 mg mixed tocotrienols experienced > 34% increase in hair numbers over eight months, while those receiving placebo experienced a slight decrease in hair numbers.

Beoy LA, Woei WJ, Hay YK. Effects of tocotrienol supplementation on hair growth in human volunteers. Tropical life sciences research. Dec 2010;21(2):91-99. https://tinyurl.com/yanntohp

 

Selenium intake is important for healthy hair follicle function, and selenium deficiency may play a role in hair loss.

Yes, iron is important – one study found lowest ferritin levels were associated with most severe hair loss. Assessment of iron status, and iron supplementation if necessary, can be considered in women with hair loss.  like the spa tone product which is easy on the digestive tract.  You could also add in lactoferrin as well to aid absorption and improve iron levels.

Rasheed H, Mahgoub D, Hegazy R, El-Komy M, Abdel Hay R, Hamid MA, Hamdy E. Serum ferritin and vitamin d in female hair loss: do they play a role? Skin Pharmacol Physiol. 2013;26(2):101-107. https://tinyurl.com/yd3el73q

 

This is a good paper on the condition and autoimmunity – it highlights the key link with thyroid autoimmune conditions.

Abi et al. Alopecia areats & autoimmunity: a clinical study. Indian J Dermatol. 2008; 53(2): 70–74. https://tinyurl.com/yaq2q57b

 

This paper includes comments on gut health as being important.

Skogberg et al. Mechanisms of tolerance and potential therapeutic interventions in Alopecia Areata. Pharmacol Ther. 2017 Nov;179:102-110. doi: 10.1016/j.pharmthera.2017.05.008. https://tinyurl.com/yd46ybjy

 

SUGGESTED SUPPLEMENTS

The following supplements are suggested for you to consider in light of your relevant expertise and intimate understanding of the needs of your client or patient. They may be used in isolation or as part of a multi supplement strategy, but at all times the consideration of their use should be tied into the specific needs of the individual you are responsible for.

Immune modulation

Vitamin D3 Complete (ARG) – take 1 daily – https://tinyurl.com/jqx3ttt

Nutritional support

Bio-3B-G (Special B Complex) (BRC) – take 2 twice daily

Zn-Zyme (BRC) – take 1 daily – https://tinyurl.com/lnlffjd

Arthred Collagen powder (ARG) – take 1tbsp twice daily – https://tinyurl.com/j2arfe4

Whey Protein Concentrate (BRC) – take 1 serving daily – https://tinyurl.com/j39tt95

Laktoferrin with Colostrum (ARG) – take 2 daily – https://tinyurl.com/jsq55kx

Tocomin SupraBio Tocotrienols (ARG) – take 1 daily – http://tinyurl.com/jv9pntj

 

I hope this helps answer your question

Christine

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