Hughes Syndrome

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    • #1258
      Joanne Crovini

      Hi there,
      I am wondering if anyone has any experience of clients with Hughes Syndrome trying to conceive?
      Thank you, Joanne

      Posted By Joanne Crovini 28/11/17






    • #1259
      Christine Bailey

      Dear Joanne

      Many thanks for your question about Hughes Syndrome.  This is more commonly known as Antiphospholipid Syndrome (APS). It is a condition that affects the blood and makes it more likely to clot than normal – a thrombophilia. This can lead to unwanted blood clots (called thromboses) forming within blood vessels.

      Pregnant women with APS are at high risk of complications – A blood clot in the placenta for example can cause problems in pregnancy such as repeated miscarriage, stillbirth, pre-eclampsia, premature delivery and growth restriction.  It is an autoimmune condition and can also result in problems in other organs including the heart, kidneys, skin, brain, eyes etc. It can also be linked to infertility.

      In many cases it is also linked to other autoimmune conditions and is known as secondary APS. This is APS that is associated with another disease, such as a rheumatic disease that affects either the bones, joints or soft tissues. An example is systemic lupus erythematosus (SLE, or lupus). SLE seems to be the disease most commonly associated with APS.

      Many of the rheumatic diseases (including SLE) that are associated with APS are autoimmune diseases.   As it is an autoimmune condition you may wish to look at underlying triggers and whether there are associated conditions. I presume your client is on some blood thinning medication – in which case it is important to check any supplements or dietary recommendations to ensure they do not interfere with medication.

      There is an association in some cases with gluten and APS – therefore either consider testing for gluten and cross-reactive foods (array 3 and 4) or remove gluten and dairy from her diet.

      Jorge et al. [Celiac disease associated with antiphospholipid syndrome].  Rev Esp Enferm Dig. 2008 Feb;100(2):102-3.


      In addition, consider running a viral screen or if indicated a stool test. There are cases where the trigger has been linked to such infections

      Abdel-Wahab, et al. Risk of developing antiphospholipid antibodies following viral infection: a systematic review and meta-analysis. Lupus. 2017 Jan 1:961203317731532. doi: 10.1177/0961203317731532.


      I would also consider measuring vitamin D levels as keeping the levels optimal can help reduce the risk of development additional autoimmune conditions as well as supporting gut barrier function. At this stage you could consider supplements to lowering inflammation but without additional details on your client it is difficult to advise you further.


      The following supplements are suggested for you to consider in light of your relevant expertise and intimate understanding of the needs of your client or patient. They may be used in isolation or as part of a multi supplement strategy, but at all times the consideration of their use should be tied into the specific needs of the individual you are responsible for.

      Lower inflammation / Immune modulation

      Arthred Collagen powder (ARG) – take 1tbsp three times a day –

      KappArest (BRC) – take 2 with each meal –

      Bio-D-Mulsion Forte (BRC) – take 1-2 drops daily based on lab testing -

      Probiotic support

      Lactobacillus GG Culturelle (ARG) – take 1 capsule three times a day –

      Saccharomyces boulardii (ARG) – take 1 capsules twice daily –

      I hope this helps answer your question



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